Type III secretion system

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf protein secretion system
gptkbp:alsoKnownAs gptkb:injectisome
gptkbp:component bacterial virulence
gptkbp:composedOf gptkb:translocon
basal body
needle complex
gptkbp:discoveredIn 1990s
gptkbp:enables bacteria to evade host immune response
bacteria to manipulate host cell functions
gptkbp:encodedBy pathogenicity islands
gptkbp:foundIn Gram-negative bacteria
gptkbp:function translocate effector proteins into host cells
https://www.w3.org/2000/01/rdf-schema#label Type III secretion system
gptkbp:inhibitedBy small molecule inhibitors
gptkbp:orthologIn bacterial flagellum
gptkbp:powerSource ATP hydrolysis
gptkbp:relatedTo flagellar apparatus
gptkbp:requires pathogenesis in many bacteria
gptkbp:secretes effector proteins
chaperones
translocators
gptkbp:structure syringe-like apparatus
gptkbp:studiedBy microbiologists
gptkbp:target antibacterial drug development
gptkbp:usedBy gptkb:Salmonella
gptkb:Pseudomonas
gptkb:Yersinia
gptkb:Shigella
gptkb:Bacteria
gptkbp:visualizes electron microscopy
gptkbp:bfsParent gptkb:Shigella_flexneri
gptkbp:bfsLayer 6