|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
connectin
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:C-terminusLocatedAt
|
M-line
|
|
gptkbp:discoveredBy
|
Kuan Wang
|
|
gptkbp:discoveredIn
|
1977
|
|
gptkbp:domain
|
immunoglobulin-like domain
fibronectin type III domain
|
|
gptkbp:encodedBy
|
TTN gene
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
cardiac muscle
smooth muscle
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
sarcomere
|
|
gptkbp:function
|
muscle elasticity
sarcomere assembly
|
|
gptkbp:gene
|
gptkb:TTN
|
|
gptkbp:GO
|
GO:0030018
|
|
gptkbp:hasIsoform
|
multiple
|
|
gptkbp:hasLongestGeneName
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Titin
|
|
gptkbp:interactsWith
|
gptkb:actin
gptkb:myosin
obscurin
muscle LIM protein
telethonin
|
|
gptkbp:largestKnownProtein
|
true
|
|
gptkbp:length
|
~27,000 to 33,000 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_2q31
|
|
gptkbp:molecularWeight
|
~3,000 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:dilated_cardiomyopathy
hereditary myopathy with early respiratory failure
tibial muscular dystrophy
|
|
gptkbp:N-terminusLocatedAt
|
gptkb:Z-disc
|
|
gptkbp:notableFor
|
longest word in English (systematic name)
|
|
gptkbp:OMIM
|
188840
|
|
gptkbp:PDB
|
1TIT
|
|
gptkbp:role
|
signal transduction
passive stiffness of muscle
sarcomere stability
|
|
gptkbp:structure
|
modular protein
|
|
gptkbp:systematicNameLength
|
189,819 letters
|
|
gptkbp:UniProtID
|
Q8WZ42
|
|
gptkbp:bfsParent
|
gptkb:Askunu
gptkb:ANKRD1
|
|
gptkbp:bfsLayer
|
7
|