Thymosin beta-4 (Tβ4)

GPTKB entity

Statements (50)
Predicate Object
gptkbp:instanceOf gptkb:protein
peptide
gptkbp:category gptkb:thymosin
cytoskeletal protein
biological regulator
gptkbp:discoveredBy Allan Goldstein
gptkbp:discoveredIn 1966
gptkbp:expressedIn gptkb:leukocytes
various tissues
platelets
gptkbp:foundIn human body
gptkbp:function wound healing
angiogenesis
cell migration
actin binding
anti-inflammatory activity
gptkbp:gene TMSB4X
https://www.w3.org/2000/01/rdf-schema#label Thymosin beta-4 (Tβ4)
gptkbp:length 43 amino acids
gptkbp:locatedOnChromosome Xq21.3-q22
gptkbp:molecularWeight 4964 Da
gptkbp:role cell differentiation
cell proliferation
angiogenesis
immune response regulation
neuroprotection
liver regeneration
tissue repair
apoptosis inhibition
extracellular matrix remodeling
angiogenic factor
anti-fibrotic activity
anti-microbial activity
cardiac repair
corneal wound healing
hair growth promotion
inflammation modulation
myocardial repair
ocular surface healing
scar reduction
stem cell recruitment
gptkbp:sequence SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
gptkbp:UniProtID P62328
gptkbp:usedIn cardiology
clinical research
dermatology
ophthalmology
regenerative medicine
gptkbp:bfsParent gptkb:RegeneRx_Biopharmaceuticals
gptkbp:bfsLayer 7