Statements (87)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
3
|
| gptkbp:bfsParent |
gptkb:Celgene_Corporation
|
| gptkbp:activities |
immunomodulatory
|
| gptkbp:approves |
gptkb:healthcare_organization
gptkb:1998 gptkb:United_States leprosy |
| gptkbp:availability |
prescription only
|
| gptkbp:clinical_trial |
Phase II
Phase III NC T00003880 NC T00004200 NC T00005759 NC T00006183 NC T00006373 NC T00006500 NC T00006700 NC T00006800 NC T00006900 NC T00007000 |
| gptkbp:contraindication |
pregnancy
breastfeeding severe renal impairment severe liver impairment history of thromboembolic events hypersensitivity to thalidomide |
| gptkbp:developed_by |
gptkb:Celgene_Corporation
|
| gptkbp:discovered_by |
gptkb:Chemie_Grünenthal
|
| gptkbp:dosage_form |
gptkb:beer
|
| gptkbp:effective_date |
2006-12-26
|
| https://www.w3.org/2000/01/rdf-schema#label |
Thalomid
|
| gptkbp:ingredients |
gptkb:thalidomide
C13 H10 N2 O4 |
| gptkbp:interacts_with |
anticoagulants
antiretrovirals CY P450 inducers CY P450 inhibitors other immunomodulatory drugs |
| gptkbp:invention |
gptkb:2015
|
| gptkbp:is_atype_of |
L04 A X02
|
| gptkbp:is_monitored_by |
thromboembolic events
liver function tests renal function blood counts |
| gptkbp:is_used_for |
gptkb:healthcare_organization
leprosy |
| gptkbp:legal_issue |
prescription only
|
| gptkbp:manager |
oral
|
| gptkbp:manufacturer |
gptkb:Celgene_Corporation
|
| gptkbp:marketed_as |
gptkb:legislation
gptkb:Australia gptkb:Japan gptkb:United_States gptkb:Native_American_tribe gptkb:Thalomid gptkb:thalidomide |
| gptkbp:packaging |
gptkb:beer
blister pack |
| gptkbp:related_to |
gptkb:lenalidomide
gptkb:thalidomide gptkb:pomalidomide |
| gptkbp:side_effect |
gptkb:fandom
fatigue headache nausea vomiting rash drowsiness insomnia constipation peripheral neuropathy blood clots thrombocytopenia thromboembolism neutropenia teratogenicity |
| gptkbp:social_structure |
C13 H10 N2 O4
|
| gptkbp:storage |
room temperature
protected from light protected from moisture |
| gptkbp:traded_on |
gptkb:Thalomid
|
| gptkbp:type_of |
50-35-1
|
| gptkbp:wildlife |
use with caution in elderly patients
use with caution in patients with diabetes use with caution in patients with infections use with caution in patients with a history of depression |