|
gptkbp:instanceOf
|
gptkb:atrial_septal_defect
gptkb:disease
|
|
gptkbp:affects
|
children
infants
cardiovascular system
|
|
gptkbp:associatedWith
|
gptkb:22q11.2_deletion_syndrome
JAG1 gene mutation
NKX2-5 gene mutation
|
|
gptkbp:causedBy
|
congenital malformation
|
|
gptkbp:complication
|
gptkb:arrhythmia
brain abscess
infective endocarditis
|
|
gptkbp:firstDescribed
|
1888
|
|
gptkbp:frequency
|
3 per 10,000 live births
|
|
gptkbp:hasComponent
|
gptkb:pulmonary_stenosis
gptkb:ventricular_septal_defect
right ventricular hypertrophy
overriding aorta
|
|
gptkbp:hasDiagnosticMethod
|
gptkb:chest_X-ray
echocardiogram
cardiac catheterization
|
|
gptkbp:hasEpidemiology
|
most common cyanotic heart defect
|
|
gptkbp:hasOrphanetID
|
Orphanet:705
|
|
gptkbp:hasTreatmentGoal
|
correct anatomical defects
improve oxygenation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tetralogy of Fallot
|
|
gptkbp:ICD-10_code
|
Q21.3
|
|
gptkbp:inheritance
|
sporadic
rarely autosomal dominant
|
|
gptkbp:MeSH_ID
|
D013728
|
|
gptkbp:mortalityRate
|
high without treatment
low with surgical repair
|
|
gptkbp:namedAfter
|
gptkb:Étienne-Louis_Arthur_Fallot
|
|
gptkbp:OMIM
|
187500
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
improves with surgery
|
|
gptkbp:riskFactor
|
gptkb:DiGeorge_syndrome
gptkb:Down_syndrome
maternal diabetes
maternal rubella infection
|
|
gptkbp:symptom
|
cyanosis
shortness of breath
heart murmur
clubbing of fingers
|
|
gptkbp:synonym
|
gptkb:Fallot's_tetralogy
gptkb:TOF
|
|
gptkbp:treatment
|
gptkb:drug
surgical repair
|
|
gptkbp:bfsParent
|
gptkb:Shaun_White
|
|
gptkbp:bfsLayer
|
5
|