Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
cancer progression
muscular dystrophy |
| gptkbp:binds |
gptkb:actin
gptkb:integrins |
| gptkbp:contains |
rod domain
FERM domain |
| gptkbp:discoveredBy |
gptkb:Richard_Hynes
|
| gptkbp:discoveredIn |
1983
|
| gptkbp:foundIn |
eukaryotic cells
|
| gptkbp:function |
link integrins to actin cytoskeleton
|
| gptkbp:gene |
TLN1
TLN2 |
| https://www.w3.org/2000/01/rdf-schema#label |
Talins
|
| gptkbp:involvedIn |
cell adhesion
focal adhesion formation |
| gptkbp:locale |
focal adhesions
costameres |
| gptkbp:molecularWeight |
~270 kDa
|
| gptkbp:orthologIn |
present in metazoans
|
| gptkbp:regulates |
integrin activation
|
| gptkbp:bfsParent |
gptkb:Styria_(fictional)
|
| gptkbp:bfsLayer |
8
|