|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvalYear
|
1977
|
|
gptkbp:ATCCode
|
gptkb:A02BA01
|
|
gptkbp:availableOn
|
gptkb:government_agency
gptkb:tablet
injection
|
|
gptkbp:brand
|
cimetidine
|
|
gptkbp:CASNumber
|
51481-61-9
|
|
gptkbp:chemicalFormula
|
C10H16N6S
|
|
gptkbp:contraindication
|
hypersensitivity to cimetidine
|
|
gptkbp:developedBy
|
gptkb:Smith,_Kline_&_French
|
|
gptkbp:discoveredIn
|
1972
|
|
gptkbp:eliminationHalfLife
|
2 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:firstH2Blocker
|
true
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Tagamet
|
|
gptkbp:interactsWith
|
gptkb:phenytoin
gptkb:theophylline
gptkb:warfarin
gptkb:benzodiazepines
gptkb:lidocaine
propranolol
|
|
gptkbp:legalStatus
|
OTC in some countries
prescription in some countries
|
|
gptkbp:marketedAs
|
GlaxoSmithKline
|
|
gptkbp:mechanismOfAction
|
histamine H2 receptor antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:replacedBy
|
gptkb:famotidine
gptkb:ranitidine
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
diarrhea
dizziness
headache
gynecomastia
|
|
gptkbp:usedFor
|
treating gastroesophageal reflux disease
treating heartburn
treating ulcers
|
|
gptkbp:bfsParent
|
gptkb:Smith,_Kline_&_French
|
|
gptkbp:bfsLayer
|
5
|