Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:approvalYear |
2018-07-20
|
| gptkbp:ATCCode |
L01XX59
|
| gptkbp:CASNumber |
1448347-49-6
|
| gptkbp:chemicalFormula |
C28H22ClF3N6O3
|
| gptkbp:firstBook |
yes
|
| gptkbp:form |
gptkb:tablet
|
| gptkbp:genericName |
gptkb:ivosidenib
|
| https://www.w3.org/2000/01/rdf-schema#label |
TIBSOVO
|
| gptkbp:indication |
gptkb:acute_myeloid_leukemia
cholangiocarcinoma |
| gptkbp:KEGGID |
D11041
|
| gptkbp:legalStatus |
US: Rx-only
|
| gptkbp:manufacturer |
gptkb:Servier_Pharmaceuticals
|
| gptkbp:mechanismOfAction |
IDH1 inhibitor
|
| gptkbp:pregnancyCategory |
Not recommended
|
| gptkbp:prescriptionStatus |
prescription only
|
| gptkbp:PubChem_CID |
DB14724
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
diarrhea fatigue QT prolongation differentiation syndrome |
| gptkbp:target |
gptkb:isocitrate_dehydrogenase_1_(IDH1)
|
| gptkbp:UNII |
6Z5B6HVF6O
|
| gptkbp:bfsParent |
gptkb:Agios_Pharmaceuticals
|
| gptkbp:bfsLayer |
5
|