T-box domain

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith cell fate determination
developmental processes
limb development
mesoderm formation
gptkbp:binds specific DNA sequences
gptkbp:conservedIn animals
fungi
plants
gptkbp:discoveredIn 1990s
gptkbp:foundIn T-box transcription factors
gptkbp:function transcription regulation
DNA binding
https://www.w3.org/2000/01/rdf-schema#label T-box domain
gptkbp:InterPro IPR001699
gptkbp:length about 180 amino acids
gptkbp:mutationAssociatedWith gptkb:cancer
congenital disorders
gptkbp:namedAfter Brachyury (T) gene
gptkbp:proteinFamily PF00907
gptkbp:structure helix-turn-helix motif
gptkbp:bfsParent gptkb:Brachyury_gene
gptkbp:bfsLayer 7