Systematic Evolution of Ligands by Exponential Enrichment

URI: https://gptkb.org/entity/Systematic_Evolution_of_Ligands_by_Exponential_Enrichment
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf biochemical technique
gptkbp:abbreviation gptkb:SELEX
gptkbp:alternativeName in vitro selection
gptkbp:application biosensors
drug discovery
therapeutics
diagnostics
gptkbp:developedBy gptkb:Larry_Gold
gptkb:Craig_Tuerk
1990
gptkbp:field gptkb:biotechnology
molecular biology
https://www.w3.org/2000/01/rdf-schema#label Systematic Evolution of Ligands by Exponential Enrichment
gptkbp:method combinatorial chemistry
gptkbp:output high-affinity ligands
gptkbp:processor amplification
enrichment
iterative selection
gptkbp:publicationYear 1990
gptkbp:publishedIn gptkb:Science_(journal)
gptkbp:relatedTo aptamer technology
in vitro selection
gptkbp:selectsFor aptamers
gptkbp:target cells
nucleic acids
proteins
small molecules
gptkbp:usedFor identifying oligonucleotides with high affinity to targets
gptkbp:uses gptkb:polymerase_chain_reaction
reverse transcription
binding assays
gptkbp:bfsParent gptkb:SELEX_(Systematic_Evolution_of_Ligands_by_Exponential_Enrichment)
gptkbp:bfsLayer 7