SELEX (Systematic Evolution of Ligands by Exponential Enrichment)

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf biochemical method
gptkbp:abbreviation gptkb:Systematic_Evolution_of_Ligands_by_Exponential_Enrichment
gptkbp:alternativeName in vitro selection
gptkbp:appliesTo gptkb:gene
peptide ligands
gptkbp:developedBy gptkb:Larry_Gold
gptkb:Craig_Tuerk
1990
gptkbp:enrichesFor high-affinity binders
https://www.w3.org/2000/01/rdf-schema#label SELEX (Systematic Evolution of Ligands by Exponential Enrichment)
gptkbp:methodStep amplification
binding selection
library generation
repetition of selection cycles
gptkbp:processor in vitro selection
gptkbp:publicationYear 1990
gptkbp:publishedIn gptkb:science
gptkbp:relatedTo in vitro evolution
aptamer
gptkbp:selectsFor nucleic acid sequences with high affinity
gptkbp:usedFor aptamer selection
identification of nucleic acid ligands
gptkbp:usedIn gptkb:biotechnology
molecular biology
drug discovery
diagnostics
gptkbp:bfsParent gptkb:SOMAmer_technology
gptkbp:bfsLayer 6