Sphingolipid delta(4)-desaturase DES1
GPTKB entity
Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
DEGS1 protein
delta(4)-desaturase, sphingolipid 1 |
| gptkbp:associatedWith |
hypomyelinating leukodystrophy 18
|
| gptkbp:biologicalProcess |
oxidoreductase activity
sphingolipid biosynthetic process |
| gptkbp:Entrez_Gene_ID |
8560
|
| gptkbp:enzymeCommissionNumber |
1.14.19.17
|
| gptkbp:function |
catalyzes the introduction of a double bond at the delta(4) position of sphingolipids
|
| gptkbp:gene |
DEGS1
|
| https://www.w3.org/2000/01/rdf-schema#label |
Sphingolipid delta(4)-desaturase DES1
|
| gptkbp:locatedOnChromosome |
1q21.3
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:product |
ceramide
|
| gptkbp:proteinFamily |
fatty acid desaturase family
|
| gptkbp:RefSeq |
NM_003676
|
| gptkbp:substrate |
dihydroceramide
|
| gptkbp:UniProtID |
O15121
|
| gptkbp:bfsParent |
gptkb:SGPS3
|
| gptkbp:bfsLayer |
8
|