Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:hereditary_spastic_paraplegia
|
| gptkbp:biologicalProcess |
ATPase activity
microtubule binding |
| gptkbp:discoveredBy |
2000
|
| gptkbp:encodedBy |
SPAST gene
|
| gptkbp:Entrez_Gene_ID |
6683
|
| gptkbp:function |
microtubule severing
|
| gptkbp:length |
530 amino acids (short isoform)
616 amino acids (long isoform) |
| gptkbp:locale |
gptkb:endoplasmic_reticulum
gptkb:cytoplasm |
| gptkbp:locatedOnChromosome |
2p22.3
|
| gptkbp:mutationAssociatedWith |
causes spastic paraplegia type 4 (SPG4)
|
| gptkbp:OMIM |
604277
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
present in many eukaryotes
|
| gptkbp:structure |
contains AAA ATPase domain
|
| gptkbp:UniProtID |
Q9UBP0
|
| gptkbp:bfsParent |
gptkb:ATPases_Associated_with_diverse_cellular_Activities
|
| gptkbp:bfsLayer |
7
|
| https://www.w3.org/2000/01/rdf-schema#label |
Spastin
|