|
gptkbp:instanceOf
|
benzodiazepine
sedative
general anesthetic
|
|
gptkbp:aroma
|
odorless
|
|
gptkbp:ATCCode
|
N01AF03
|
|
gptkbp:brand
|
gptkb:Pentothal
|
|
gptkbp:CASNumber
|
71-73-8
|
|
gptkbp:chemicalFormula
|
C11H17N2NaO2S
|
|
gptkbp:color
|
white
|
|
gptkbp:contraindication
|
porphyria
hypersensitivity to barbiturates
|
|
gptkbp:country_of_ban
|
gptkb:European_Union
gptkb:Germany
gptkb:Italy
gptkb:United_Kingdom
|
|
gptkbp:discoveredBy
|
gptkb:Donalee_L._Tabern
gptkb:Ernest_H._Volwiler
|
|
gptkbp:discoveredIn
|
1934
|
|
gptkbp:eliminationHalfLife
|
5-11 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sodium thiopental
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
GABA-A receptor agonist
|
|
gptkbp:meltingPoint
|
162 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
264.32 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
CHEMBL1201192
16641
DB00599
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:sideEffect
|
hypotension
respiratory depression
cardiac depression
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:synonym
|
gptkb:thiopental_sodium
gptkb:sodium_pentothal
|
|
gptkbp:UNII
|
I4744080IR
|
|
gptkbp:used_in
|
gptkb:veterinary_medicine
truth serum (colloquial)
electroconvulsive therapy (historically)
|
|
gptkbp:usedFor
|
euthanasia
status epilepticus
lethal injection
sedation
induction of anesthesia
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Lethal_Injection
|
|
gptkbp:bfsLayer
|
6
|