|
gptkbp:instanceOf
|
vaccine
|
|
gptkbp:administeredBy
|
intradermal injection
bifurcated needle
|
|
gptkbp:alternativeName
|
Jennerian vaccine
vaccinia vaccine
|
|
gptkbp:approvedBy
|
gptkb:World_Health_Organization
|
|
gptkbp:associatedWith
|
gptkb:ACAM2000
gptkb:Dryvax
Modified Vaccinia Ankara (MVA)
|
|
gptkbp:boosterRecommended
|
every 3-5 years (for at-risk individuals)
|
|
gptkbp:category
|
live vaccine
|
|
gptkbp:contains
|
gptkb:vaccinia_virus
live virus
|
|
gptkbp:contributedTo
|
global health
eradication of smallpox
eradication certified in 1980
|
|
gptkbp:developedBy
|
gptkb:Edward_Jenner
|
|
gptkbp:durationOfImmunity
|
3-5 years (strong), longer (partial)
|
|
gptkbp:effect
|
high
|
|
gptkbp:excludes
|
smallpox virus
|
|
gptkbp:historicalSignificance
|
first successful vaccine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Smallpox Vaccine
|
|
gptkbp:includedIn
|
WHO Essential Medicines List (historically)
|
|
gptkbp:introducedIn
|
1796
|
|
gptkbp:lastRoutineUse
|
1970s
|
|
gptkbp:notRecommendedFor
|
pregnant women
immunocompromised individuals
people with eczema
|
|
gptkbp:notRoutinelyGiven
|
since smallpox eradication
|
|
gptkbp:prevention
|
gptkb:smallpox
|
|
gptkbp:relatedTo
|
gptkb:cowpox
variolation
|
|
gptkbp:riskFactor
|
gptkb:military
emergency responders (in some countries)
laboratory workers handling orthopoxviruses
|
|
gptkbp:routeOfAdministration
|
intradermal
percutaneous
|
|
gptkbp:sideEffect
|
gptkb:eczema_vaccinatum
gptkb:postvaccinal_encephalitis
gptkb:progressive_vaccinia
fever
rash
swollen lymph nodes
|
|
gptkbp:stockpiledBy
|
governments
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:usedFor
|
biodefense
|
|
gptkbp:usedIn
|
ring vaccination strategy
|
|
gptkbp:usedInEradicationCampaign
|
1967-1977
|
|
gptkbp:WHOStatus
|
no longer routinely administered
|
|
gptkbp:bfsParent
|
gptkb:Vaccination_Scar
|
|
gptkbp:bfsLayer
|
7
|