Signal 2 (costimulatory signal)
GPTKB entity
Statements (16)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
immunology concept
|
| gptkbp:absenceLeadsTo |
T cell anergy
|
| gptkbp:distinctFrom |
Signal 1 (antigen-specific signal)
|
| gptkbp:example |
CD28-B7 interaction
|
| https://www.w3.org/2000/01/rdf-schema#label |
Signal 2 (costimulatory signal)
|
| gptkbp:importantFor |
adaptive immune response
|
| gptkbp:involves |
gptkb:CD28
B7-1 (CD80) B7-2 (CD86) |
| gptkbp:mediatedBy |
costimulatory molecules
|
| gptkbp:partOf |
T cell activation
|
| gptkbp:requires |
full T cell activation
|
| gptkbp:usedBetween |
cell surface receptor
antigen-presenting cell |
| gptkbp:bfsParent |
gptkb:Signal_1
|
| gptkbp:bfsLayer |
8
|