|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:approves
|
gptkb:1997
multiple countries
|
|
gptkbp:availability
|
prescription only
|
|
gptkbp:brand
|
gptkb:Sibutramine
gptkb:Reductil
gptkb:Meridia
|
|
gptkbp:chemical_formula
|
C17 H26 Cl N
|
|
gptkbp:class
|
anorectic agent
|
|
gptkbp:clinical_trial
|
various studies
|
|
gptkbp:contraindication
|
gptkb:Cardiology
pregnancy
breastfeeding
|
|
gptkbp:dosage_form
|
gptkb:capsule
10 mg to 15 mg daily
|
|
gptkbp:formulation
|
oral capsule
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Sibutrex
|
|
gptkbp:ingredients
|
sibutramine
|
|
gptkbp:interacts_with
|
antidepressants
monoamine oxidase inhibitors
other weight loss medications
|
|
gptkbp:invention
|
patented
|
|
gptkbp:market_position
|
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:marketed_as
|
various pharmaceutical companies
|
|
gptkbp:mechanism_of_action
|
gptkb:depression
|
|
gptkbp:related_to
|
obesity treatment
|
|
gptkbp:safety_measures
|
risk of cardiovascular events
not for use in children
monitoring required for long-term use
|
|
gptkbp:side_effect
|
insomnia
constipation
dry mouth
increased heart rate
|
|
gptkbp:used_for
|
weight loss
|
|
gptkbp:weight
|
285.85 g/mol
|
|
gptkbp:withdrawn_year
|
gptkb:2010
|
|
gptkbp:bfsParent
|
gptkb:Sibutramine
|
|
gptkbp:bfsLayer
|
6
|