|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
gptkb:ALS
schizophrenia
neurodegenerative diseases
|
|
gptkbp:biologicalProcess
|
dehydratase activity
racemase activity
|
|
gptkbp:catalyzes
|
conversion of L-serine to D-serine
conversion of D-serine to L-serine
|
|
gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
|
gptkbp:discoveredBy
|
1999
|
|
gptkbp:EC_number
|
5.1.1.18
|
|
gptkbp:Entrez_Gene_ID
|
63826
|
|
gptkbp:expressedIn
|
neurons
astrocytes
|
|
gptkbp:foundIn
|
gptkb:kidney
brain
liver
|
|
gptkbp:gene
|
gptkb:SRR
|
|
gptkbp:gene_location_(human)
|
gptkb:chromosome_17
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Serine Racemase
|
|
gptkbp:inhibition_by
|
malonate
hydroxylamine
L-serine O-sulfate
|
|
gptkbp:involves
|
D-serine biosynthesis
NMDA receptor regulation
|
|
gptkbp:locatedOnChromosome
|
17q20.3
|
|
gptkbp:OMIM
|
606277
|
|
gptkbp:orthologIn
|
gptkb:mouse
gptkb:zebrafish
right
|
|
gptkbp:pathway
|
gptkb:glycine,_serine_and_threonine_metabolism
neurotransmitter regulation
|
|
gptkbp:PDB
|
3L6B
|
|
gptkbp:product
|
gptkb:D-serine
gptkb:L-serine
gptkb:pyruvate
ammonia
|
|
gptkbp:regulates
|
gptkb:ATP
phosphorylation
Mg2+
nitrosylation
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:D-serine
gptkb:L-serine
|
|
gptkbp:UniProtID
|
gptkb:O43175
|
|
gptkbp:bfsParent
|
gptkb:SRR
|
|
gptkbp:bfsLayer
|
5
|