Selamectin

GPTKB entity

Statements (34)
Predicate Object
gptkbp:instanceOf antiparasitic drug
macrocyclic lactone
gptkbp:approvedBy 1999
veterinary use
gptkbp:ATCCode QP54AA05
gptkbp:brand gptkb:Stronghold
revolutionary
gptkbp:CASNumber 220119-17-5
gptkbp:chemicalFormula C43H63NO11
gptkbp:compatibleWith human use
gptkbp:discoveredBy gptkb:Pfizer
https://www.w3.org/2000/01/rdf-schema#label Selamectin
gptkbp:KEGGID gptkb:D08513
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction causes paralysis and death of parasites
increases chloride ion permeability in nerve cells of parasites
gptkbp:molecularWeight 769.963 g/mol
gptkbp:PubChem_CID gptkb:CHEMBL190836
9571041
gptkbp:relatedTo gptkb:moxidectin
gptkb:ivermectin
gptkbp:routeOfAdministration topical
gptkbp:sideEffect hair loss at application site
digestive upset
neurological signs (rare)
gptkbp:UNII 2P6O2G2K98
gptkbp:usedFor treatment of ear mites in cats and dogs
treatment of fleas in cats and dogs
treatment of heartworm in cats and dogs
treatment of hookworms in cats
treatment of roundworms in cats
treatment of sarcoptic mange in dogs
gptkbp:bfsParent gptkb:Heartworms
gptkbp:bfsLayer 7