Statements (34)
Predicate | Object |
---|---|
gptkbp:instanceOf |
antiparasitic drug
macrocyclic lactone |
gptkbp:approvedBy |
1999
veterinary use |
gptkbp:ATCCode |
QP54AA05
|
gptkbp:brand |
gptkb:Stronghold
revolutionary |
gptkbp:CASNumber |
220119-17-5
|
gptkbp:chemicalFormula |
C43H63NO11
|
gptkbp:compatibleWith |
human use
|
gptkbp:discoveredBy |
gptkb:Pfizer
|
https://www.w3.org/2000/01/rdf-schema#label |
Selamectin
|
gptkbp:KEGGID |
gptkb:D08513
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
causes paralysis and death of parasites
increases chloride ion permeability in nerve cells of parasites |
gptkbp:molecularWeight |
769.963 g/mol
|
gptkbp:PubChem_CID |
gptkb:CHEMBL190836
9571041 |
gptkbp:relatedTo |
gptkb:moxidectin
gptkb:ivermectin |
gptkbp:routeOfAdministration |
topical
|
gptkbp:sideEffect |
hair loss at application site
digestive upset neurological signs (rare) |
gptkbp:UNII |
2P6O2G2K98
|
gptkbp:usedFor |
treatment of ear mites in cats and dogs
treatment of fleas in cats and dogs treatment of heartworm in cats and dogs treatment of hookworms in cats treatment of roundworms in cats treatment of sarcoptic mange in dogs |
gptkbp:bfsParent |
gptkb:Heartworms
|
gptkbp:bfsLayer |
7
|