|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
SPAK
STE20/SPS1-related proline-alanine-rich kinase
|
|
gptkbp:associatedWith
|
hypertension
|
|
gptkbp:discoveredBy
|
Delpire et al.
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodes
|
SPAK protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000101191
27347
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
heart
|
|
gptkbp:fullName
|
serine/threonine kinase 39
|
|
gptkbp:function
|
protein kinase activity
regulation of blood pressure
regulation of ion transport
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:HGNC_ID
|
HGNC:11425
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
STK39
|
|
gptkbp:length
|
547 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 2
2q24.3
|
|
gptkbp:molecularWeight
|
62 kDa
|
|
gptkbp:mutationAssociatedWith
|
essential hypertension
|
|
gptkbp:OMIM
|
604984
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Stk39
|
|
gptkbp:phosphorylates
|
gptkb:SLC12A3
SLC12A2
|
|
gptkbp:regulates
|
Na+-K+-2Cl- cotransporter
WNK signaling pathway
|
|
gptkbp:UniProtID
|
O94804
|
|
gptkbp:bfsParent
|
gptkb:STORK-7
gptkb:chromosome_2q35
|
|
gptkbp:bfsLayer
|
7
|