SSRI discontinuation syndrome
GPTKB entity
Statements (44)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
medical condition
|
| gptkbp:alsoKnownAs |
SSRI withdrawal syndrome
|
| gptkbp:associatedWith |
gptkb:selective_serotonin_reuptake_inhibitors
|
| gptkbp:cause |
abrupt cessation of SSRI medication
|
| gptkbp:differentialDiagnosis |
anxiety disorder
other withdrawal syndromes relapse of depression |
| gptkbp:DSM-5 |
not specifically classified
|
| gptkbp:duration |
usually days to weeks
|
| gptkbp:field |
gptkb:pharmacy
psychiatry |
| gptkbp:firstDescribed |
1990s
|
| gptkbp:guideline |
taper SSRIs slowly to prevent
|
| https://www.w3.org/2000/01/rdf-schema#label |
SSRI discontinuation syndrome
|
| gptkbp:ICD-10_code |
not specifically classified
|
| gptkbp:notableFeature |
more common with short-acting SSRIs
not due to addiction symptoms resolve with SSRI reinstatement |
| gptkbp:occurredIn |
gptkb:citalopram
gptkb:escitalopram gptkb:fluvoxamine gptkb:paroxetine gptkb:sertraline gptkb:fluoxetine |
| gptkbp:prevalence |
varies by SSRI and patient
|
| gptkbp:riskFactor |
high dose SSRIs
long-term SSRI use short half-life SSRIs |
| gptkbp:symptom |
mood swings
nausea anxiety dizziness fatigue headache insomnia irritability flu-like symptoms sensory disturbances electric shock sensations |
| gptkbp:treatment |
gradual tapering of SSRI
reinstating SSRI switching to longer half-life SSRI |
| gptkbp:bfsParent |
gptkb:discontinuation_syndrome
|
| gptkbp:bfsLayer |
7
|