Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeSplicing |
yes
|
| gptkbp:associatedWith |
gptkb:Legius_syndrome
|
| gptkbp:chromosomeArm |
15q14
|
| gptkbp:discoveredIn |
2002
|
| gptkbp:encodes |
gptkb:SPRED1_protein
|
| gptkbp:Entrez_Gene_ID |
161742
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
negative regulation of Ras/MAPK signaling pathway
|
| gptkbp:HGNC_ID |
HGNC:15541
|
| https://www.w3.org/2000/01/rdf-schema#label |
SPRED1 gene
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_15
|
| gptkbp:mutationAssociatedWith |
developmental disorders
|
| gptkbp:OMIM |
609291
|
| gptkbp:orthologInMouse |
Spred1
|
| gptkbp:proteinFamily |
gptkb:EVH1_domain
gptkb:SPRED_family gptkb:SPR_domain c-Kit binding domain |
| gptkbp:regulates |
cell differentiation
cell proliferation cell migration |
| gptkbp:UniProtID |
Q7Z699
|
| gptkbp:bfsParent |
gptkb:RTK-RAS_pathway
|
| gptkbp:bfsLayer |
6
|