Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
xCT
|
| gptkbp:associatedWith |
oxidative stress response
ferroptosis regulation |
| gptkbp:component |
system Xc- antiporter
|
| gptkbp:encodes |
Solute carrier family 7 member 11 protein
|
| gptkbp:Entrez_Gene_ID |
23657
ENSG00000151012 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:function |
cystine/glutamate transporter
|
| gptkbp:HGNC_ID |
HGNC:18713
|
| https://www.w3.org/2000/01/rdf-schema#label |
SLC7A11
|
| gptkbp:involvedIn |
amino acid transport
glutathione biosynthesis |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_4
|
| gptkbp:OMIM |
607936
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Mus_musculus
gptkb:Rattus_norvegicus |
| gptkbp:overexpressedIn |
certain cancers
|
| gptkbp:proteinFamily |
gptkb:solute_carrier_family
|
| gptkbp:publicTransit |
amino acid transporter
|
| gptkbp:regulates |
downregulated by p53
upregulated by NRF2 |
| gptkbp:UniProtID |
Q9UPY5
|
| gptkbp:bfsParent |
gptkb:solute_carrier_family
|
| gptkbp:bfsLayer |
6
|