Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Skp1-Cullin-F-box complex
SCF ubiquitin ligase |
| gptkbp:component |
F-box protein
Cullin1 Rbx1 Skp1 |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:F-box_protein_example |
gptkb:FBXW7
Skp2 β-TrCP |
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:fullName |
Skp, Cullin, F-box containing complex
|
| gptkbp:function |
E3 ubiquitin ligase
protein ubiquitination regulation of protein degradation |
| gptkbp:GO_term |
GO:0019005
|
| https://www.w3.org/2000/01/rdf-schema#label |
SCF Complex
|
| gptkbp:PDB |
1LDK
|
| gptkbp:regulates |
signal transduction
transcription cell cycle |
| gptkbp:relatedTo |
ubiquitin-proteasome system
|
| gptkbp:requires |
gptkb:ATP
gptkb:E2_ubiquitin-conjugating_enzyme |
| gptkbp:target |
phosphorylated proteins
|
| gptkbp:bfsParent |
gptkb:Auxin_Signaling
|
| gptkbp:bfsLayer |
7
|