Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:CASNumber |
280744-09-4
|
| gptkbp:hasMolecularFormula |
C17H11Cl2N3O2
|
| gptkbp:hasSMILES |
CN1C=CC2=C1C=CC(=C2)C3=CC(=O)NC(=O)C3C4=C(C=C(C=C4)Cl)Cl
|
| https://www.w3.org/2000/01/rdf-schema#label |
SB216763
|
| gptkbp:inhibitedBy |
glycogen synthase kinase-3 (GSK-3)
|
| gptkbp:is_not_soluble_in |
gptkb:water
|
| gptkbp:is_used_in_research_on |
gptkb:Alzheimer's_disease
gptkb:cancer gptkb:diabetes |
| gptkbp:isSolubleIn |
gptkb:DMSO
gptkb:methanol ethanol |
| gptkbp:IUPACName |
gptkb:3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
|
| gptkbp:mechanismOfAction |
ATP-competitive inhibitor
|
| gptkbp:meltingPoint |
>200°C
|
| gptkbp:molecularWeight |
360.2 g/mol
|
| gptkbp:PubChem_CID |
5311293
CHEMBL12360 |
| gptkbp:target |
gptkb:GSK-3α
gptkb:GSK-3β |
| gptkbp:bfsParent |
gptkb:SB-216763
|
| gptkbp:bfsLayer |
7
|