|
gptkbp:instanceOf
|
gptkb:chemical_compound
dietary supplement
|
|
gptkbp:abbreviation
|
gptkb:AdoMet
gptkb:SAM
|
|
gptkbp:approvedBy
|
gptkb:Europe
|
|
gptkbp:availableOn
|
intravenous injection
oral supplement
tablet form
capsule form
|
|
gptkbp:CASNumber
|
29908-03-0
|
|
gptkbp:chemicalFormula
|
C15H22N6O5S
|
|
gptkbp:class
|
nutraceutical
amino acid derivative
methyl donor
|
|
gptkbp:contraindication
|
bipolar disorder
|
|
gptkbp:discoveredBy
|
gptkb:Giulio_Cantoni
|
|
gptkbp:foundIn
|
human body
|
|
gptkbp:fullName
|
gptkb:S-adenosyl_methionine
|
|
gptkbp:hasRole
|
gptkb:coenzyme
methyl donor
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
SAMe
|
|
gptkbp:interactsWith
|
gptkb:MAO_inhibitors
antidepressants
|
|
gptkbp:involvedIn
|
transsulfuration pathway
methylation reactions
polyamine synthesis
|
|
gptkbp:isDiscoveredIn
|
1952
|
|
gptkbp:isMetabolizedTo
|
gptkb:S-adenosylhomocysteine
|
|
gptkbp:isNotApprovedIn
|
United States (as prescription drug)
|
|
gptkbp:isSynthesizedFrom
|
gptkb:ATP
methionine
|
|
gptkbp:producedBy
|
brain
liver
all mammalian tissues
|
|
gptkbp:requires
|
synthesis of nucleic acids
synthesis of neurotransmitters
synthesis of phospholipids
synthesis of hormones
|
|
gptkbp:sells
|
over-the-counter supplement
|
|
gptkbp:sideEffect
|
anxiety
insomnia
gastrointestinal upset
|
|
gptkbp:studiedBy
|
gptkb:Alzheimer's_disease
fibromyalgia
cholestasis
HIV-associated myelopathy
|
|
gptkbp:usedFor
|
treatment of depression
treatment of liver disease
treatment of osteoarthritis
|
|
gptkbp:bfsParent
|
gptkb:Gnosis_Limited
gptkb:S-Adenosyl_methionine_(SAMe)
gptkb:SAM_E
|
|
gptkbp:bfsLayer
|
7
|