S. cerevisiae Sec61p

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName Sec61 alpha subunit
YLR378C protein
gptkbp:component gptkb:Sec61_complex
gptkbp:foundIn gptkb:Saccharomyces_cerevisiae
gptkbp:function protein translocation
forms translocon channel
gptkbp:gene SEC61
gptkbp:GO:0005788 endoplasmic reticulum lumen
gptkbp:GO:0005789 endoplasmic reticulum membrane
gptkbp:GO:0006614 SRP-dependent cotranslational protein targeting to membrane
https://www.w3.org/2000/01/rdf-schema#label S. cerevisiae Sec61p
gptkbp:interactsWith Sbh1p
Sec62p
Sec63p
Sss1p
gptkbp:involvedIn gptkb:ER-associated_degradation_(ERAD)
protein targeting to ER
gptkbp:location endoplasmic reticulum membrane
gptkbp:locusTag YLR378C
gptkbp:molecularWeight ~53 kDa
gptkbp:orthologIn human SEC61A1
gptkbp:requires co-translational translocation
gptkbp:transmembraneDomains 10
gptkbp:UniProtID P32368
gptkbp:bfsParent gptkb:Sec61_alpha
gptkbp:bfsLayer 8