Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
statin medication
|
| gptkbp:approvalYear |
2003
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
gptkb:C10AA07
|
| gptkbp:brand |
gptkb:Crestor
|
| gptkbp:CASNumber |
287714-41-4
|
| gptkbp:chemicalClass |
pyrimidine derivative
|
| gptkbp:contraindication |
gptkb:liver_disease
pregnancy |
| gptkbp:discoveredBy |
gptkb:Shionogi
|
| gptkbp:eliminationHalfLife |
19 hours
|
| gptkbp:hasMolecularFormula |
C22H28FN3O6S
|
| https://www.w3.org/2000/01/rdf-schema#label |
Rosuvastatin
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
HMG-CoA reductase inhibitor
|
| gptkbp:metabolism |
gptkb:CYP2C9
gptkb:CYP2C19 |
| gptkbp:pregnancyCategory |
gptkb:X_(US)
|
| gptkbp:proteinBinding |
88%
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
muscle pain
liver enzyme abnormalities diabetes risk |
| gptkbp:usedFor |
lowering cholesterol
prevention of cardiovascular disease |
| gptkbp:bfsParent |
gptkb:ANTIAS
gptkb:C10AA gptkb:Zentiva gptkb:Statins |
| gptkbp:bfsLayer |
7
|