Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:activities |
increases cell turnover
prevents clogged pores |
| gptkbp:approves |
gptkb:1971
|
| gptkbp:brand |
gptkb:tretinoin
|
| gptkbp:clinical_trial |
effective for acne
effective for hyperpigmentation effective for wrinkles |
| gptkbp:contraindication |
pregnancy
breastfeeding |
| gptkbp:dosage_form |
0.025% cream
0.05% cream 0.1% cream |
| gptkbp:effective_date |
FDA approved
|
| gptkbp:formulation |
gptkb:tablet
gptkb:skincare_product |
| gptkbp:frequency |
once daily
|
| https://www.w3.org/2000/01/rdf-schema#label |
Retin-A
|
| gptkbp:ingredients |
gptkb:tretinoin
|
| gptkbp:interacts_with |
avoid using with harsh skin products
avoid using with other retinoids may increase sensitivity to other medications |
| gptkbp:is_used_for |
gptkb:skincare_product
anti-aging treatment |
| gptkbp:manufacturer |
gptkb:Johnson_&_Johnson
|
| gptkbp:pharmacokinetics |
excreted in urine
metabolized in liver absorbed through skin topically applied |
| gptkbp:population |
teenagers
adults not recommended for children |
| gptkbp:products |
gptkb:adapalene
gptkb:isotretinoin gptkb:tazarotene |
| gptkbp:requires |
prescription required
|
| gptkbp:scholarships |
avoid sun exposure
moisturize skin apply at night start with lower concentration use sunscreen |
| gptkbp:side_effect |
skin irritation
swelling dry skin redness stinging itching burning sensation peeling skin |
| gptkbp:storage |
room temperature
|
| gptkbp:bfsParent |
gptkb:Valeant_Pharmaceuticals
|
| gptkbp:bfsLayer |
6
|