|
gptkbp:instanceOf
|
gptkb:cancer
gptkb:disease
|
|
gptkbp:affects
|
gptkb:kidney
|
|
gptkbp:alternativeName
|
hypernephroma
renal adenocarcinoma
|
|
gptkbp:associatedWith
|
gptkb:VHL_gene_mutation
|
|
gptkbp:diagnosedBy
|
gptkb:CT_scan
MRI
biopsy
|
|
gptkbp:firstDescribed
|
1883
|
|
gptkbp:hasBiomarker
|
gptkb:CAIX
gptkb:PAX8
|
|
gptkbp:hasCellOfOrigin
|
renal tubular epithelial cell
|
|
gptkbp:hasGenderPrevalence
|
more common in males
|
|
gptkbp:hasImagingFeature
|
enhancing mass on contrast CT
|
|
gptkbp:hasMetastasisSite
|
gptkb:cancer
gptkb:bone
brain
liver
|
|
gptkbp:hasParaneoplasticSyndrome
|
gptkb:hypercalcemia
gptkb:Stauffer_syndrome
hypertension
polycythemia
|
|
gptkbp:histology
|
clear cytoplasm in clear cell subtype
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Renal cell carcinoma
|
|
gptkbp:ICD-10_code
|
gptkb:C64
|
|
gptkbp:incidence
|
~400,000 new cases per year worldwide
|
|
gptkbp:medianAge
|
60 years
|
|
gptkbp:mortalityRate
|
~175,000 deaths per year worldwide
|
|
gptkbp:prevalence
|
most common kidney cancer in adults
|
|
gptkbp:prognosis
|
variable
|
|
gptkbp:riskFactor
|
gptkb:von_Hippel-Lindau_disease
family history
obesity
smoking
hypertension
chronic kidney disease
|
|
gptkbp:stageName
|
gptkb:TNM
|
|
gptkbp:subspecies
|
chromophobe renal cell carcinoma
clear cell renal cell carcinoma
papillary renal cell carcinoma
|
|
gptkbp:symptom
|
hematuria
abdominal mass
flank pain
|
|
gptkbp:treatment
|
surgery
radiation therapy
chemotherapy
immunotherapy
targeted therapy
|
|
gptkbp:bfsParent
|
gptkb:Clear_cell_carcinoma
|
|
gptkbp:bfsLayer
|
6
|