Renal cell carcinoma

GPTKB entity

Statements (54)
Predicate Object
gptkbp:instance_of gptkb:healthcare_organization
gptkbp:bfsLayer 5
gptkbp:bfsParent gptkb:Left_kidney
gptkbp:affects kidney
gptkbp:associated_with gptkb:von_Hippel-Lindau_disease
gptkb:tuberous_sclerosis
hereditary leiomyomatosis
gptkbp:clinical_trial NC T00012345
NC T00067890
NC T00123456
NC T00234567
NC T00345678
gptkbp:genetic_diversity gptkb:MET_gene_mutation
gptkb:VHL_gene_mutation
FLCN gene mutation
https://www.w3.org/2000/01/rdf-schema#label Renal cell carcinoma
gptkbp:is_often_used_in adults
men
older adults
gptkbp:lifespan leading cause of cancer death
gptkbp:number_of_stages stage I
stage IV
stage II
stage III
gptkbp:occurs_in increasing incidence
gptkbp:origin renal tubular epithelium
gptkbp:research ongoing clinical trials
biomarker studies
novel therapies
gptkbp:risk_factor hypertension
obesity
smoking
gptkbp:screenings not routinely screened
gptkbp:social_responsibility gptkb:MRI
CT scan
biopsy
5-year survival rate
poor prognosis in advanced stages
gptkbp:symptoms fatigue
weight loss
hematuria
flank pain
gptkbp:treatment gptkb:hospital
gptkb:vaccine
radiation therapy
targeted therapy
recurrence is common after treatment
response to immunotherapy varies
surgical resection is curative in early stages
targeted therapies improve survival
gptkbp:type gptkb:chromophobe_carcinoma
gptkb:clear_cell_carcinoma
gptkb:collecting_duct_carcinoma
gptkb:papillary_carcinoma