Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:medicine
|
| gptkbp:application |
treatment of viral infections
treatment of cancer treatment of genetic diseases |
| gptkbp:approved_drug |
gptkb:Givosiran
Patisiran |
| gptkbp:deliveredBy |
lipid nanoparticles
viral vectors |
| gptkbp:first_FDA_approval |
2018
|
| https://www.w3.org/2000/01/rdf-schema#label |
RNA interference therapy
|
| gptkbp:involves |
small interfering RNA
short hairpin RNA |
| gptkbp:mechanismOfAction |
gene silencing
|
| gptkbp:regulates |
gptkb:gene
|
| gptkbp:relatedTo |
antisense therapy
|
| gptkbp:researchArea |
neurodegenerative diseases
rare diseases |
| gptkbp:sideEffect |
immune response
off-target effects |
| gptkbp:target |
gene expression
|
| gptkbp:uses |
gptkb:RNA_interference
|
| gptkbp:bfsParent |
gptkb:transthyretin_mRNA
|
| gptkbp:bfsLayer |
8
|