Statements (23)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:REV-ERB_agonist
                                        
                                         gptkb:synthetic_compound  | 
                            
| gptkbp:administeredBy | 
                                    
                                        
                                            
                                            mice
                                        
                                        
                                         | 
                            
| gptkbp:CASNumber | 
                                    
                                        
                                            
                                            1379686-29-9
                                        
                                        
                                         | 
                            
| gptkbp:chemicalClass | 
                                    
                                        
                                            
                                            benzoxazepine derivative
                                        
                                        
                                         | 
                            
| gptkbp:compatibleWith | 
                                    
                                        
                                            
                                            human use
                                        
                                        
                                         | 
                            
| gptkbp:developedBy | 
                                    
                                        
                                            gptkb:Scripps_Research_Institute
                                        
                                         | 
                            
| gptkbp:effect | 
                                    
                                        
                                            
                                            reduced fat mass
                                        
                                        
                                         improved exercise capacity increased energy expenditure  | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            
                                            REV-ERB nuclear receptor agonism
                                        
                                        
                                         | 
                            
| gptkbp:modulatedBy | 
                                    
                                        
                                            
                                            metabolism
                                        
                                        
                                         circadian rhythm  | 
                            
| gptkbp:relatedTo | 
                                    
                                        
                                            
                                            SR9009
                                        
                                        
                                         | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:studiedBy | 
                                    
                                        
                                            
                                            obesity
                                        
                                        
                                         inflammation metabolic disorders  | 
                            
| gptkbp:target | 
                                    
                                        
                                            gptkb:REV-ERBα
                                        
                                         gptkb:REV-ERBβ  | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:SR_90001
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            8
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            REV-ERB agonist SR9001
                                        
                                        
                                         |