Quinine

GPTKB entity

Statements (56)
Predicate Object
gptkbp:instanceOf gptkb:drug
alkaloid
gptkbp:ATCCode P01BC01
gptkbp:CASNumber 130-95-0
gptkbp:chemical_compound C20H24N2O2
gptkbp:color white
gptkbp:contraindication gptkb:G6PD_deficiency
gptkb:myasthenia_gravis
pregnancy
optic neuritis
tinnitus
gptkbp:derivedFrom gptkb:cinchona_bark
gptkbp:discoveredBy gptkb:Charles_Marie_de_La_Condamine
gptkbp:eliminationHalfLife 11 hours
gptkbp:excretion urine
gptkbp:firstIsolatedFrom 1820
gptkbp:flavor bitter
gptkbp:foundIn gptkb:South_American_cinchona_trees
cocktail
https://www.w3.org/2000/01/rdf-schema#label Quinine
gptkbp:IUPACName gptkb:(R)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol
gptkbp:legalStatus prescription only
gptkbp:meltingPoint 177°C
gptkbp:metabolism liver
gptkbp:molecularWeight 324.42 g/mol
gptkbp:PubChem_CID 3034034
CHEMBL45
DB00468
gptkbp:relatedTo cinchonidine
cinchonine
quinidine
gptkbp:riskFactor gptkb:hypoglycemia
thrombocytopenia
allergic reactions
cinchonism
gptkbp:routeOfAdministration oral
intramuscular
intravenous
gptkbp:sideEffect gptkb:arrhythmia
nausea
headache
hemolysis
ringing in the ears
vision disturbances
gptkbp:solubility slightly soluble in water
soluble in alcohol
gptkbp:UNII K72T3FS567
gptkbp:usedAs analgesic
anti-inflammatory
antipyretic
gptkbp:usedFor treatment of malaria
treatment of babesiosis
gptkbp:usedIn bitter flavoring in beverages
historical antimalarial therapy
gptkbp:bfsParent gptkb:Tonic
gptkbp:bfsLayer 6