gptkbp:instanceOf
|
gptkb:drug
alkaloid
|
gptkbp:ATCCode
|
P01BC01
|
gptkbp:CASNumber
|
130-95-0
|
gptkbp:chemical_compound
|
C20H24N2O2
|
gptkbp:color
|
white
|
gptkbp:contraindication
|
gptkb:G6PD_deficiency
gptkb:myasthenia_gravis
pregnancy
optic neuritis
tinnitus
|
gptkbp:derivedFrom
|
gptkb:cinchona_bark
|
gptkbp:discoveredBy
|
gptkb:Charles_Marie_de_La_Condamine
|
gptkbp:eliminationHalfLife
|
11 hours
|
gptkbp:excretion
|
urine
|
gptkbp:firstIsolatedFrom
|
1820
|
gptkbp:flavor
|
bitter
|
gptkbp:foundIn
|
gptkb:South_American_cinchona_trees
cocktail
|
https://www.w3.org/2000/01/rdf-schema#label
|
Quinine
|
gptkbp:IUPACName
|
gptkb:(R)-(6-methoxyquinolin-4-yl)((2S,4S,5R)-5-vinylquinuclidin-2-yl)methanol
|
gptkbp:legalStatus
|
prescription only
|
gptkbp:meltingPoint
|
177°C
|
gptkbp:metabolism
|
liver
|
gptkbp:molecularWeight
|
324.42 g/mol
|
gptkbp:PubChem_CID
|
3034034
CHEMBL45
DB00468
|
gptkbp:relatedTo
|
cinchonidine
cinchonine
quinidine
|
gptkbp:riskFactor
|
gptkb:hypoglycemia
thrombocytopenia
allergic reactions
cinchonism
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
gptkbp:sideEffect
|
gptkb:arrhythmia
nausea
headache
hemolysis
ringing in the ears
vision disturbances
|
gptkbp:solubility
|
slightly soluble in water
soluble in alcohol
|
gptkbp:UNII
|
K72T3FS567
|
gptkbp:usedAs
|
analgesic
anti-inflammatory
antipyretic
|
gptkbp:usedFor
|
treatment of malaria
treatment of babesiosis
|
gptkbp:usedIn
|
bitter flavoring in beverages
historical antimalarial therapy
|
gptkbp:bfsParent
|
gptkb:Tonic
|
gptkbp:bfsLayer
|
6
|