|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:Transmembrane_protein_106B
TMEM106B_HUMAN
|
|
gptkbp:associatedWith
|
neurodegeneration
frontotemporal dementia
frontotemporal lobar degeneration
|
|
gptkbp:discoveredBy
|
2004
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000361390
91972
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
liver
|
|
gptkbp:function
|
involved in lysosomal function
|
|
gptkbp:gene
|
gptkb:TMEM106B
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:GO_term
|
gptkb:GO:0005764
GO:0005515
GO:0016021
GO:0005768
|
|
gptkbp:HGNC_ID
|
HGNC:24658
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Q8N1N4
|
|
gptkbp:length
|
274
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_7
|
|
gptkbp:location
|
7p21.3
|
|
gptkbp:molecularWeight
|
31 kDa
|
|
gptkbp:mutationAssociatedWith
|
risk factor for FTLD
|
|
gptkbp:numberOfExons
|
9
|
|
gptkbp:OMIM
|
613413
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Q5XI73
gptkb:Q8C0I1
|
|
gptkbp:pathway
|
protein processing in endoplasmic reticulum
lysosome pathway
|
|
gptkbp:PDB
|
gptkb:7Q6A
gptkb:7Q6B
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:RefSeq
|
NP_001243025.1
|
|
gptkbp:reviewedBy
|
gptkb:UniProtKB/Swiss-Prot
|
|
gptkbp:subcellularLocation
|
integral membrane protein
lysosome membrane
|
|
gptkbp:transmembraneDomains
|
present
|
|
gptkbp:UniProtID
|
gptkb:Q8N1N4
|
|
gptkbp:bfsParent
|
gptkb:SLC6A51
|
|
gptkbp:bfsLayer
|
7
|