|
gptkbp:instanceOf
|
Cell
neurons
|
|
gptkbp:axonType
|
myelinated
|
|
gptkbp:cellBodySize
|
large
|
|
gptkbp:dendrites
|
extensive dendritic arbor
|
|
gptkbp:developedBy
|
derived from ventricular zone
|
|
gptkbp:discoveredBy
|
gptkb:Jan_Evangelista_Purkyně
|
|
gptkbp:electrophysiology
|
complex spikes
simple spikes
|
|
gptkbp:firstDescribed
|
1837
|
|
gptkbp:foundIn
|
gptkb:cerebellum
|
|
gptkbp:function
|
motor coordination
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Purkyně cells
|
|
gptkbp:inhibitory
|
true
|
|
gptkbp:input
|
climbing fibers
parallel fibers
|
|
gptkbp:location
|
gptkb:Purkinje_layer
|
|
gptkbp:marking
|
gptkb:calbindin
gptkb:parvalbumin
gptkb:GAD67
|
|
gptkbp:modulatedBy
|
gptkb:endocannabinoids
gptkb:GABA
gptkb:acetylcholine
gptkb:histamine
glutamate
dopamine
norepinephrine
serotonin
glycine
nitric oxide
purines
neuropeptides
|
|
gptkbp:morphologicalType
|
planar dendritic tree
|
|
gptkbp:namedAfter
|
gptkb:Jan_Evangelista_Purkyně
|
|
gptkbp:neurotransmitter
|
gptkb:GABA
|
|
gptkbp:notableProject
|
to cerebellar nuclei
|
|
gptkbp:numberInHumanBrain
|
~15 million
|
|
gptkbp:output
|
gptkb:deep_cerebellar_nuclei
inhibitory synapses
|
|
gptkbp:outputNeurotransmitter
|
gptkb:GABA
|
|
gptkbp:pathology
|
affected in autism spectrum disorders
affected in multiple system atrophy
affected in spinocerebellar ataxia
degeneration in ataxias
|
|
gptkbp:role
|
cerebellar cortex
|
|
gptkbp:shape
|
large flask-shaped
|
|
gptkbp:species
|
vertebrates
|
|
gptkbp:stainedBy
|
gptkb:Golgi_stain
|
|
gptkbp:synapticInputs
|
most in CNS
|
|
gptkbp:bfsParent
|
gptkb:Jan_Evangelista_Purkyně
|
|
gptkbp:bfsLayer
|
6
|