|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:drug
|
|
gptkbp:abusePotential
|
moderate
|
|
gptkbp:ATCCode
|
R01BA02
|
|
gptkbp:bioavailability
|
90-100%
|
|
gptkbp:brand
|
gptkb:Sudafed
gptkb:Actifed
gptkb:Contac
|
|
gptkbp:CASNumber
|
90-82-4
|
|
gptkbp:chemicalFormula
|
C10H15NO
|
|
gptkbp:combines
|
gptkb:ibuprofen
gptkb:paracetamol
antihistamines
|
|
gptkbp:contraindication
|
severe hypertension
severe coronary artery disease
|
|
gptkbp:controlledSubstanceStatus
|
regulated due to use in methamphetamine synthesis
|
|
gptkbp:discoveredIn
|
1889
|
|
gptkbp:eliminationHalfLife
|
4.3-8 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:foundIn
|
gptkb:Ephedra_plant
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pseudoephedrine
|
|
gptkbp:IUPACName
|
(1S,2S)-2-methylamino-1-phenylpropan-1-ol
|
|
gptkbp:legalStatus
|
prescription only (in some countries)
over-the-counter (in some countries)
|
|
gptkbp:mechanismOfAction
|
alpha-adrenergic receptor agonist
beta-adrenergic receptor agonist
|
|
gptkbp:meltingPoint
|
119-120°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
165.23 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201209
7028
CHEBI:8495
DB00852
|
|
gptkbp:relatedTo
|
gptkb:ephedrine
amphetamine
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
dizziness
nervousness
insomnia
palpitations
increased blood pressure
|
|
gptkbp:synonym
|
(+)-pseudoephedrine
threo-2-methylamino-1-phenylpropan-1-ol
|
|
gptkbp:UNII
|
YB0K5M7B3E
|
|
gptkbp:usedFor
|
nasal congestion
allergic rhinitis
sinus congestion
common cold
|
|
gptkbp:bfsParent
|
gptkb:Guaifenesin
|
|
gptkbp:bfsLayer
|
7
|