Protein Tyrosine Phosphatase
GPTKB entity
Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:activeSiteResidue |
cysteine
|
| gptkbp:biologicalProcess |
phosphoprotein phosphatase activity
|
| gptkbp:catalyzes |
removal of phosphate group from tyrosine residue
|
| gptkbp:cofactor |
none required
|
| gptkbp:discoveredBy |
gptkb:Edwin_G._Krebs
gptkb:Edmond_H._Fischer |
| gptkbp:EC_number |
3.1.3.48
|
| gptkbp:encodedBy |
gptkb:PTP_gene_family
|
| gptkbp:foundIn |
eukaryotes
|
| gptkbp:hasGOFunction |
gptkb:GO:0004725
|
| https://www.w3.org/2000/01/rdf-schema#label |
Protein Tyrosine Phosphatase
|
| gptkbp:inhibitedBy |
pervanadate
vanadate |
| gptkbp:involvedIn |
gptkb:diabetes
signal transduction autoimmune diseases immune response oncogenesis |
| gptkbp:PDB |
gptkb:1PTY
gptkb:2HNQ |
| gptkbp:regulates |
cell differentiation
metabolism cell growth cell signaling cell cycle |
| gptkbp:relatedTo |
gptkb:protein
|
| gptkbp:subclassOf |
non-receptor protein tyrosine phosphatase
receptor-type protein tyrosine phosphatase |
| gptkbp:substrate |
phosphotyrosine-containing proteins
|
| gptkbp:bfsParent |
gptkb:PTP
|
| gptkbp:bfsLayer |
5
|