|
gptkbp:instanceOf
|
hormone
|
|
gptkbp:ATCCode
|
G03BA04
|
|
gptkbp:biosynthesized_from
|
cholesterol
|
|
gptkbp:CASNumber
|
145-13-1
|
|
gptkbp:category
|
endocrinology
hormones
neurosteroids
cholestanes
pregnanes
|
|
gptkbp:chemicalFormula
|
C21H32O2
|
|
gptkbp:discoveredBy
|
gptkb:Adolf_Butenandt
gptkb:Edward_Adelbert_Doisy
1934
|
|
gptkbp:foundIn
|
gptkb:skin
gptkb:adrenal_gland
brain
liver
gonads
|
|
gptkbp:hasRole
|
neurosteroid
metabolic intermediate
hormone precursor
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pregnenolone
|
|
gptkbp:IUPACName
|
3β-hydroxypregn-5-en-20-one
|
|
gptkbp:meltingPoint
|
191–193 °C
|
|
gptkbp:MeSH_ID
|
D011287
|
|
gptkbp:metabolism
|
gptkb:CYP17A1
gptkb:3β-hydroxysteroid_dehydrogenase
|
|
gptkbp:molecularWeight
|
316.48 g/mol
|
|
gptkbp:predecessor
|
gptkb:progesterone
gptkb:aldosterone
gptkb:estradiol
cortisol
testosterone
|
|
gptkbp:producedBy
|
gptkb:placenta
brain
adrenal cortex
gonads
|
|
gptkbp:PubChem_CID
|
8955
CHEBI:16581
CHEMBL1182
DB02789
|
|
gptkbp:routeOfAdministration
|
oral
topical
sublingual
|
|
gptkbp:solubility
|
insoluble in water
soluble in ethanol
soluble in ether
soluble in chloroform
|
|
gptkbp:synonym
|
P5
3β-hydroxy-5-pregnen-20-one
delta-5-pregnen-3β-ol-20-one
|
|
gptkbp:UNII
|
19GJ9Q6S8F
|
|
gptkbp:bfsParent
|
gptkb:Cholesterol
|
|
gptkbp:bfsLayer
|
6
|