|
gptkbp:instanceOf
|
gptkb:drug
oxime
|
|
gptkbp:administeredBy
|
gptkb:diazepam
atropine
|
|
gptkbp:ATCCode
|
V03AB03
|
|
gptkbp:CASNumber
|
94-91-7
|
|
gptkbp:chemicalClass
|
pyridinium compound
|
|
gptkbp:contraindication
|
hypersensitivity
|
|
gptkbp:discoveredBy
|
gptkb:Irwin_Wilson
|
|
gptkbp:discoveredIn
|
1955
|
|
gptkbp:eliminationHalfLife
|
0.8–2 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C7H9N2O
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pralidoxime
|
|
gptkbp:includedIn
|
gptkb:WHO_Model_List_of_Essential_Medicines
|
|
gptkbp:IUPACName
|
(E)-1-methyl-2-[(hydroxyimino)methyl]pyridin-1-ium
|
|
gptkbp:KEGGID
|
D08413
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
reactivates acetylcholinesterase
|
|
gptkbp:meltingPoint
|
220–222 °C
|
|
gptkbp:MeSH_ID
|
D011225
|
|
gptkbp:metabolism
|
renal
|
|
gptkbp:pregnancyCategory
|
C (US)
B2 (Australia)
|
|
gptkbp:PubChem_CID
|
4738
4908
CHEMBL1201
DB00733
|
|
gptkbp:routeOfAdministration
|
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
headache
hypertension
blurred vision
tachycardia
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:synonym
|
gptkb:2-PAM
gptkb:Protopam
|
|
gptkbp:UNII
|
8NRQ6R6U1J
|
|
gptkbp:usedFor
|
pesticide poisoning
nerve agent poisoning
organophosphate poisoning
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Antidotes
gptkb:Antidote
|
|
gptkbp:bfsLayer
|
5
|