|
gptkbp:instanceOf
|
gptkb:chemical_compound
acetylcholinesterase reactivator
|
|
gptkbp:actsOn
|
gptkb:acetylcholinesterase
|
|
gptkbp:administeredBy
|
intramuscular injection
intravenous injection
|
|
gptkbp:antidote
|
pesticide poisoning
nerve agent poisoning
|
|
gptkbp:ATCCode
|
V03AB03
|
|
gptkbp:CASNumber
|
55-97-0
|
|
gptkbp:category
|
antidote
oxime
cholinesterase reactivator
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
|
|
gptkbp:developedBy
|
gptkb:U.S._Army
|
|
gptkbp:discoveredIn
|
1950s
|
|
gptkbp:eliminationHalfLife
|
0.8–2 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasInChIKey
|
YQXDHQYHLASQIW-UHFFFAOYSA-M
|
|
gptkbp:hasMolecularFormula
|
C7H9N2O
|
|
gptkbp:hasSMILES
|
C1=CC=NC=[N+](C1)C=NO.Cl-
|
|
gptkbp:hasUNII
|
2J3S5XWA9S
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
2-PAM
|
|
gptkbp:IUPACName
|
1-[(2-hydroxyiminomethyl)pyridinium]methanide chloride
|
|
gptkbp:KEGGID
|
D00409
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:meltingPoint
|
220–221 °C
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
4738
4908
DB00733
CHEBI:8234
|
|
gptkbp:restored
|
acetylcholinesterase activity
|
|
gptkbp:routeOfAdministration
|
intramuscular
subcutaneous
intravenous
|
|
gptkbp:sideEffect
|
nausea
hypertension
blurred vision
tachycardia
|
|
gptkbp:synonym
|
gptkb:pralidoxime
|
|
gptkbp:usedFor
|
treatment of organophosphate poisoning
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:Pralidoxime
|
|
gptkbp:bfsLayer
|
6
|