Potassium voltage-gated channel subfamily Q member 1

URI: https://gptkb.org/entity/Potassium_voltage-gated_channel_subfamily_Q_member_1
GPTKB entity
Statements (45)
Predicate Object
gptkbp:instanceOf gptkb:protein
ion channel
gptkbp:alternativeName gptkb:Kv7.1
KVLQT1
gptkbp:associatedWith gptkb:Jervell_and_Lange-Nielsen_syndrome
gptkb:Long_QT_syndrome
familial atrial fibrillation
short QT syndrome
gptkbp:biologicalProcess cardiac muscle contraction
voltage-gated potassium channel activity
regulation of membrane potential
gptkbp:discoveredBy 1996
gptkbp:Entrez_Gene_ID gptkb:ENSG00000053918
gptkb:KCNQ1
gptkbp:expressedIn heart
pancreas
inner ear
gptkbp:formsComplexWith gptkb:KCNE1
gptkb:KCNE3
gptkbp:foundIn gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkb:Rattus_norvegicus
gptkbp:function potassium ion transport
regulation of cardiac action potential
gptkbp:gene gptkb:KCNQ1
gptkbp:HGNC_ID 6294
https://www.w3.org/2000/01/rdf-schema#label Potassium voltage-gated channel subfamily Q member 1
gptkbp:length 676
gptkbp:locatedIn gptkb:cell_membrane
gptkbp:locatedOnChromosome gptkb:11p15.5
gptkbp:molecularWeight 75 kDa
gptkbp:mutationAssociatedWith gptkb:arrhythmia
deafness
prolonged QT interval
gptkbp:OMIM 607542
gptkbp:orthologInMouse gptkb:Kcnq1
gptkbp:PDB gptkb:6V01
gptkbp:RefSeq gptkb:NM_000218
gptkbp:regulates insulin secretion
epithelial ion transport
gptkbp:subunit tetramer
gptkbp:transmembraneDomains 6
gptkbp:UniProtID P51787
gptkbp:bfsParent gptkb:Kcnq1
gptkbp:bfsLayer 7