Potassium voltage-gated channel subfamily E member 1

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	minK IsK
gptkbp:associatedWith	gptkb:Jervell_and_Lange-Nielsen_syndrome gptkb:Long_QT_syndrome
gptkbp:component	gptkb:IKs_channel
gptkbp:Entrez_Gene_ID	ENSG00000155846
gptkbp:expressedIn	gptkb:cancer gptkb:skeletal_muscle gptkb:kidney gptkb:placenta brain liver pancreas
gptkbp:firstDescribed	1986
gptkbp:foundIn	heart inner ear
gptkbp:function	modulates potassium channel activity regulates cardiac action potential
gptkbp:gene	gptkb:KCNE1
gptkbp:geneType	protein-coding
gptkbp:HGNC_ID	gptkb:HGNC:6257
https://www.w3.org/2000/01/rdf-schema#label	Potassium voltage-gated channel subfamily E member 1
gptkbp:interactsWith	gptkb:KCNQ1
gptkbp:length	129
gptkbp:locatedIn	gptkb:human_chromosome_21
gptkbp:locatedOnChromosome	21q22.12
gptkbp:molecularWeight	15 kDa
gptkbp:mutationAssociatedWith	gptkb:arrhythmia congenital deafness
gptkbp:numberOfExons	3
gptkbp:OMIM	176261
gptkbp:orthologInMouse	gptkb:Kcne1
gptkbp:PDB	2K21
gptkbp:proteinFamily	gptkb:KCNE_family
gptkbp:RefSeq	gptkb:NM_000219
gptkbp:regulates	cardiac repolarization
gptkbp:reviewedBy	gptkb:GeneReviews gptkb:OMIM gptkb:UniProt
gptkbp:subunit	gptkb:potassium_channel_complex
gptkbp:transmembraneDomains	true
gptkbp:UniProtID	gptkb:P15382
gptkbp:bfsParent	gptkb:KCNE1
gptkbp:bfsLayer	7