|
gptkbp:instanceOf
|
gptkb:autoimmune_disease
gptkb:skin
|
|
gptkbp:affects
|
gptkb:skin
mucous membranes
|
|
gptkbp:autoantibodyTarget
|
gptkb:desmoglein_1
gptkb:desmoglein_3
|
|
gptkbp:causedBy
|
autoantibodies
|
|
gptkbp:complication
|
sepsis
secondary infection
fluid loss
|
|
gptkbp:diagnosedBy
|
skin biopsy
direct immunofluorescence
ELISA for desmoglein antibodies
|
|
gptkbp:differentialDiagnosis
|
gptkb:bullous_pemphigoid
gptkb:mucous_membrane_pemphigoid
paraneoplastic pemphigus
|
|
gptkbp:firstDescribed
|
gptkb:19th_century
|
|
gptkbp:hasEpidemiology
|
slightly more common in people of Mediterranean, Jewish, or Indian descent
more common in middle-aged and older adults
|
|
gptkbp:ICD-10_code
|
L10.0
|
|
gptkbp:mortalityRate
|
potentially fatal if untreated
|
|
gptkbp:namedAfter
|
pemphigus (Greek for blister)
|
|
gptkbp:pathology
|
acantholysis
intraepidermal blister
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:symptom
|
oral ulcers
blistering
erosions
|
|
gptkbp:treatment
|
gptkb:rituximab
corticosteroids
immunosuppressants
|
|
gptkbp:bfsParent
|
gptkb:Pemphigus
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Pemphigus vulgaris
|