Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:skin
autoimmune disease |
| gptkbp:affects |
gptkb:skin
mucous membranes |
| gptkbp:autoantibodyTarget |
gptkb:desmoglein_1
gptkb:desmoglein_3 |
| gptkbp:causedBy |
autoantibodies
|
| gptkbp:complication |
sepsis
secondary infection fluid loss |
| gptkbp:diagnosedBy |
skin biopsy
direct immunofluorescence ELISA for desmoglein antibodies |
| gptkbp:differentialDiagnosis |
gptkb:bullous_pemphigoid
gptkb:mucous_membrane_pemphigoid paraneoplastic pemphigus |
| gptkbp:firstDescribed |
19th century
|
| gptkbp:hasEpidemiology |
slightly more common in people of Mediterranean, Jewish, or Indian descent
more common in middle-aged and older adults |
| https://www.w3.org/2000/01/rdf-schema#label |
Pemphigus vulgaris
|
| gptkbp:ICD-10_code |
L10.0
|
| gptkbp:mortalityRate |
potentially fatal if untreated
|
| gptkbp:namedAfter |
pemphigus (Greek for blister)
|
| gptkbp:pathology |
acantholysis
intraepidermal blister |
| gptkbp:prevalence |
rare
|
| gptkbp:symptom |
oral ulcers
blistering erosions |
| gptkbp:treatment |
gptkb:rituximab
corticosteroids immunosuppressants |
| gptkbp:bfsParent |
gptkb:Pemphigus
|
| gptkbp:bfsLayer |
7
|