|
gptkbp:instance_of
|
gptkb:depression
|
|
gptkbp:approves
|
gptkb:1992
gptkb:Australia
gptkb:Canada
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:atccode
|
N06 AB05
|
|
gptkbp:brand
|
gptkb:Seroxat
gptkb:Paxil
|
|
gptkbp:casnumber
|
61869-08-7
|
|
gptkbp:chemical_formula
|
C19 H20 FNO3 S
|
|
gptkbp:clinical_trial
|
Phase IV
|
|
gptkbp:contraindication
|
MAO inhibitors
pregnancy category D
|
|
gptkbp:discontinuation_syndrome
|
possible
|
|
gptkbp:discovered_by
|
gptkb:Glaxo_Smith_Kline
|
|
gptkbp:dosage_form
|
20 mg to 50 mg daily
|
|
gptkbp:duration
|
several months to years
|
|
gptkbp:form
|
tablets
oral suspension
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Paroxetine hydrochloride
|
|
gptkbp:interacts_with
|
gptkb:beer
gptkb:warfarin
NSAIDs
other SSRIs
|
|
gptkbp:legal_status
|
prescription only
|
|
gptkbp:lifespan
|
21 hours
|
|
gptkbp:marketed_as
|
Paxil CR
Paxil LCR
Paxil XR
|
|
gptkbp:mechanism_of_action
|
gptkb:depression
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:nutritional_value
|
95%
|
|
gptkbp:research_focus
|
gptkb:depression
anxiety
PTSD
OCD
panic disorder
|
|
gptkbp:route_of_administration
|
oral
|
|
gptkbp:side_effect
|
nausea
drowsiness
insomnia
dry mouth
sexual dysfunction
|
|
gptkbp:symptoms
|
sleep disturbances
mood swings
flu-like symptoms
electric shock sensations
|
|
gptkbp:used_for
|
gptkb:post-traumatic_stress_disorder
anxiety disorders
obsessive-compulsive disorder
major depressive disorder
panic disorder
|
|
gptkbp:bfsParent
|
gptkb:Seroxat
|
|
gptkbp:bfsLayer
|
6
|