Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:depression
|
| gptkbp:administered_by |
oral tablet
oral suspension |
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:available_on |
generic medication
|
| gptkbp:brand |
gptkb:Pexeva
gptkb:Seroxat gptkb:Paxil |
| gptkbp:can_cause |
withdrawal symptoms
serotonin syndrome |
| gptkbp:chemical_formula |
C19 H20 FNO3 S
|
| gptkbp:class |
SSRIs
|
| gptkbp:contraindication |
pregnancy
breastfeeding |
| gptkbp:developed_by |
gptkb:Smith_Kline_Beecham
|
| https://www.w3.org/2000/01/rdf-schema#label |
Paroxetine
|
| gptkbp:interacts_with |
NSAIDs
MAO inhibitors blood thinners other antidepressants |
| gptkbp:is_part_of |
gptkb:selective_serotonin_reuptake_inhibitors
|
| gptkbp:is_used_for |
gptkb:post-traumatic_stress_disorder
anxiety disorders obsessive-compulsive disorder major depressive disorder panic disorder |
| gptkbp:is_used_off_label_for |
chronic pain
social anxiety disorder eating disorders hot flashes |
| gptkbp:lifespan |
21 hours
|
| gptkbp:metabolism |
gptkb:CYP2_D6
|
| gptkbp:side_effect |
nausea
drowsiness insomnia dry mouth sexual dysfunction |
| gptkbp:suitable_for |
gptkb:children
patients with kidney disease patients with glaucoma patients with liver disease patients with seizures patients with a history of substance abuse patients with a history of depression with psychotic features patients with a history of aggression patients with a history of mania patients with a history of psychosis patients with a history of suicidal thoughts patients with bipolar disorder patients with a history of severe allergic reactions |
| gptkbp:bfsParent |
gptkb:Searle_Pharmaceuticals
|
| gptkbp:bfsLayer |
5
|