Statements (33)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | 
                                    
                                        
                                            gptkb:drug
                                        
                                         | 
                            
| gptkbp:activeIngredient | 
                                    
                                        
                                            gptkb:tapentadol
                                        
                                         | 
                            
| gptkbp:approvalYear | 
                                    
                                        
                                            
                                            2010
                                        
                                        
                                         | 
                            
| gptkbp:ATCCode | 
                                    
                                        
                                            
                                            N02AX06
                                        
                                        
                                         | 
                            
| gptkbp:contraindication | 
                                    
                                        
                                            
                                            paralytic ileus
                                        
                                        
                                         severe respiratory depression acute intoxication with alcohol  | 
                            
| gptkbp:drugClass | 
                                    
                                        
                                            gptkb:opioid
                                        
                                         | 
                            
| gptkbp:eliminationHalfLife | 
                                    
                                        
                                            
                                            4 hours
                                        
                                        
                                         | 
                            
| gptkbp:excretion | 
                                    
                                        
                                            
                                            urine
                                        
                                        
                                         | 
                            
| gptkbp:form | 
                                    
                                        
                                            
                                            prolonged-release tablet
                                        
                                        
                                         immediate-release tablet  | 
                            
| gptkbp:legalStatus | 
                                    
                                        
                                            
                                            prescription only
                                        
                                        
                                         | 
                            
| gptkbp:manufacturer | 
                                    
                                        
                                            
                                            GrĂ¼nenthal
                                        
                                        
                                         | 
                            
| gptkbp:marketedIn | 
                                    
                                        
                                            gptkb:Australia
                                        
                                         gptkb:Canada gptkb:Europe  | 
                            
| gptkbp:mechanismOfAction | 
                                    
                                        
                                            gptkb:norepinephrine_reuptake_inhibitor
                                        
                                         mu-opioid receptor agonist  | 
                            
| gptkbp:metabolism | 
                                    
                                        
                                            
                                            liver
                                        
                                        
                                         | 
                            
| gptkbp:pregnancyCategory | 
                                    
                                        
                                            gptkb:C_(Australia)
                                        
                                         C (US)  | 
                            
| gptkbp:routeOfAdministration | 
                                    
                                        
                                            
                                            oral
                                        
                                        
                                         | 
                            
| gptkbp:sideEffect | 
                                    
                                        
                                            
                                            nausea
                                        
                                        
                                         constipation dizziness somnolence  | 
                            
| gptkbp:status | 
                                    
                                        
                                            
                                            approved in EU
                                        
                                        
                                         | 
                            
| gptkbp:synonym | 
                                    
                                        
                                            gptkb:tapentadol
                                        
                                         | 
                            
| gptkbp:usedFor | 
                                    
                                        
                                            
                                            pain management
                                        
                                        
                                         | 
                            
| gptkbp:bfsParent | 
                                    
                                        
                                            gptkb:Tapentadol
                                        
                                         | 
                            
| gptkbp:bfsLayer | 
                                    
                                        
                                            
                                            7
                                        
                                        
                                         | 
                            
| https://www.w3.org/2000/01/rdf-schema#label | 
                                    
                                        
                                            
                                            Palexia
                                        
                                        
                                         |