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gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:VPS15
p150
vacuolar protein sorting 15 homolog
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gptkbp:associatedWith
|
neurodegenerative diseases (implicated)
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gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000198901
30849
|
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gptkbp:expressedIn
|
many tissues
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gptkbp:fullName
|
phosphoinositide-3-kinase regulatory subunit 4
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gptkbp:function
|
involved in autophagy
involved in vesicle-mediated transport
regulatory subunit of class III PI3K complex
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gptkbp:gene
|
gptkb:PIK3R4
|
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gptkbp:geneType
|
protein-coding
|
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gptkbp:HGNC_ID
|
HGNC:8976
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PIK3R4 (human)
|
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gptkbp:interactsWith
|
gptkb:PIK3C3
gptkb:ATG14
gptkb:UVRAG
BECN1
|
|
gptkbp:locatedOnChromosome
|
3
3q22.1
|
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gptkbp:molecularWeight
|
150 kDa
|
|
gptkbp:OMIM
|
602610
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pik3r4
|
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gptkbp:pathway
|
autophagy pathway
endocytosis pathway
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:RefSeq
|
NM_014602
NP_055386
|
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gptkbp:regulates
|
autophagosome formation
PIK3C3 kinase activity
|
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gptkbp:structure
|
contains HEAT repeats
contains WD40 repeats
|
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gptkbp:subcellularLocation
|
gptkb:endosome
gptkb:cytoplasm
autophagosome
|
|
gptkbp:UniProtID
|
Q9UKU9
|
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gptkbp:bfsParent
|
gptkb:regulatory_subunit_Vps15
|
|
gptkbp:bfsLayer
|
6
|