|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
PFK muscle type
PFK-M
phosphofructokinase, muscle type
|
|
gptkbp:associatedWith
|
Glycogen storage disease type VII (Tarui disease)
|
|
gptkbp:discoveredBy
|
1960s
|
|
gptkbp:encodes
|
phosphofructokinase, muscle type (PFK-M)
|
|
gptkbp:Entrez_Gene_ID
|
5213
|
|
gptkbp:enzymeCommissionNumber
|
2.7.1.11
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
liver (low levels)
|
|
gptkbp:fullName
|
phosphofructokinase, muscle
|
|
gptkbp:function
|
catalyzes phosphorylation of fructose-6-phosphate in glycolysis
|
|
gptkbp:HGNC_ID
|
8870
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
PFKM
|
|
gptkbp:involvedIn
|
glycolysis
|
|
gptkbp:length
|
PFK-M: 780 amino acids
|
|
gptkbp:locatedOnChromosome
|
12q13.11
|
|
gptkbp:molecularWeight
|
~85 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Tarui_disease
|
|
gptkbp:OMIM
|
171850
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Pfkm
|
|
gptkbp:product
|
phosphofructokinase, muscle type
|
|
gptkbp:RefSeq
|
NM_000289
|
|
gptkbp:regulates
|
allosterically regulated by ATP, AMP, citrate, and fructose 2,6-bisphosphate
|
|
gptkbp:subunit
|
phosphofructokinase tetramer
|
|
gptkbp:UniProtID
|
P08237
|
|
gptkbp:bfsParent
|
gptkb:Phosphofructokinase
|
|
gptkbp:bfsLayer
|
7
|