Statements (27)
Predicate | Object |
---|---|
gptkbp:instanceOf |
immunotherapy
|
gptkbp:administeredBy |
intravenous infusion
|
gptkbp:approvedBy |
gptkb:non-small_cell_lung_cancer
gptkb:urothelial_carcinoma gptkb:head_and_neck_squamous_cell_carcinoma melanoma Hodgkin lymphoma renal cell carcinoma |
gptkbp:contraindication |
severe autoimmune disease
|
gptkbp:developedBy |
gptkb:Merck_&_Co.
gptkb:Bristol-Myers_Squibb |
gptkbp:discoveredIn |
2010s
|
gptkbp:enhance |
T-cell immune response
|
gptkbp:example |
gptkb:pembrolizumab
gptkb:cemiplimab gptkb:nivolumab |
https://www.w3.org/2000/01/rdf-schema#label |
PD-1 inhibitors
|
gptkbp:mechanismOfAction |
block PD-1 pathway
|
gptkbp:regulates |
immune response
|
gptkbp:sideEffect |
diarrhea
fatigue rash immune-related adverse events |
gptkbp:target |
PD-1 protein
|
gptkbp:usedFor |
gptkb:cancer
|
gptkbp:bfsParent |
gptkb:PD-L1_expression
|
gptkbp:bfsLayer |
6
|