P9WQK1

GPTKB entity

Statements (47)
Predicate Object
gptkbp:instanceOf UniProt accession number
gptkbp:alternativeName gptkb:ANT2
gptkb:Adenine_nucleotide_translocator_2
gptkbp:associated_complex gptkb:Mitochondrial_ADP/ATP_translocase_complex
gptkbp:associatedWith Mitochondrial disease (rare cases)
gptkbp:biologicalProcess mitochondrial transport
ADP transmembrane transporter activity
ATP transmembrane transporter activity
ATP transport
nucleotide transmembrane transporter activity
gptkbp:canonical_sequence Yes
gptkbp:Entrez_Gene_ID 291
ENSP00000361624
GC09P048282
gptkbp:evidence_at_protein_level Yes
gptkbp:function Mediates exchange of ADP and ATP across mitochondrial inner membrane
gptkbp:gene gptkb:SLC25A5
gptkbp:gene_location_(GRCh37) gptkb:Xq24
gptkbp:HGNC_ID gptkb:HGNC:10992
https://www.w3.org/2000/01/rdf-schema#label P9WQK1
gptkbp:length 298
gptkbp:locatedOnChromosome gptkb:Xq24
X
gptkbp:location Mitochondrial inner membrane
gptkbp:molecularWeight 32,648
gptkbp:OMIM 300150
gptkbp:organism gptkb:Homo_sapiens
gptkbp:orthologInMouse gptkb:Slc25a5
gptkbp:pathway gptkb:Oxidative_phosphorylation
Mitochondrial ADP/ATP transport
gptkbp:postTranslationalModification Phosphorylation
Acetylation
gptkbp:protein_name gptkb:ADP/ATP_translocase_2
gptkbp:proteinFamily gptkb:Mitochondrial_carrier_family_(SLC25)
gptkb:Solute_carrier_family_25
gptkbp:RefSeq gptkb:NP_001141.2
gptkbp:sequenceStatus Reviewed
gptkbp:sequenceVersion 2
gptkbp:structure Multi-pass membrane protein
gptkbp:subcellularLocation gptkb:Mitochondrion_inner_membrane
gptkbp:tissue_specificity Expressed in many tissues, highest in heart, skeletal muscle, and testis
gptkbp:transmembraneDomains 6
gptkbp:UniProt_accession_for Human protein: SLC25A5
gptkbp:UniProt_entry_name gptkb:ADT2_HUMAN
gptkbp:UniProt_release 2024_02
gptkbp:bfsParent gptkb:DAAG
gptkbp:bfsLayer 7